Take Part

Low mood despite taking antidepressants? Two key features of depression include low motivation and difficulty feeling enjoyment. We are testing whether a medication, pramipexole, helps reduce depression more than a placebo.

PAX-D is currently recruiting at nine centres across the UK. 

              
To see a full list of participating centres, please click here.

Please contact us if you:
  • Are aged 18 years or older
  • Are experiencing depression
  • Have tried 2 or more antidepressants but still feel depressed
  • Have no previous history of psychosis, bipolar depression, or impulse control disorders

Register your interest online through Lindus Health:

For the following centres, you can register your interest to take part by answering a few short questions, and a member of the team will be in touch!

Avon and Wiltshire Mental Health Partnership NHS Foundation Trust
Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust
Mersey Care NHS Foundation Trust
Oxford Health NHS Foundation Trust
South London and Maudsley NHS Foundation Trust
 

 

For all other sites, please contact a member of the team using the details listed on the Participating Centres page.

For further information, please contact either the PAX-D team directly, or the Treatment Resistant Depression clinic using the details below:

PAX-D Team

Email: oxfordhealth.paxd@nhs.net

Telephone: 01865 618 210

 

Oxford Health Treatment Resistant Depression Clinic

Email: oxfordhealth.trdclinic@nhs.net

Telephone: 01865 902 135

Website: https://oxfordhealthbrc.nihr.ac.uk/our-work/treatment-resistant-depression/